In this research, estimation potential of Aquacrop model under deficit irrigation and sa-linity conditions were evaluated for winter wheat grown under arid and semi-arid climates. Five different irrigation strategies and irrigation water salinity levels (0.5, 5, 7.5, 10, 15 dS m-1) were taken with the model to estimate deficit irrigation and salinity scenarios. Wheat grain yield, biomass production and canopy cover were simulated under deficit and salinity stresses. According to estimation of the model; the deficit irrigation with water reduction of more than 75 % of full irrigation was applied at growth stages of wheat, revealed the significant reduction in grain yield, biomass and canopy cover as compared with full irrigation practice. The increa-se in irrigation water salinity caused a significant decrease in grain yield and biomass value. It was compared to the 0.5 dS m-1 salinity level, a low value of 3% was obtained for the 5 dS m-1 salinity level. Yield loss of 7.5, 10 and 15 dS m-1 salinity levels were found to be 18.97%, 42.5% and 85.6% respectively. Also, increasing irrigation water depth in saline treatments resulted in increased grain and biomass yield. For sustainable water management in agriculture area, using simulation model such as ...